From the north, the main line between Florence and Rome, it has a station in Terontola (on the Trasimeno Lake, Perugia, Assisi, Spello and Foligno), then coming from Florence take one of the daily trains to Terontola / Cortona (1 ‘/ 2 hr .), Which coincide with a train to Assisi / S.Maria degli Angeli (45 to 60 min.).
From the south, the main line between Rome and Ancona has a station in Foligno (Spello, Assisi, Perugia and Lake Trasimeno), then from Rome, take one of the nine daily trains on Ancona line, stop at Foligno where You can move on a train to Perugia (10 to 15 min.).
All the lines mentioned are part of the FS state rail system and stop in a station of Santa Maria degli Angeli, far away from the historic center (about 3 km) but in 30 minutes by bus you will arrive in the center of the city. Bus services depart from the square in front of the station and take you to Piazza Matteotti.
The closest major airports in the center of Italy are in Rome, Pisa, and Florence.
Assisi is not far from Rome, Pisa and Florence and is easily reachable by these two cities by train, bus or car.
The main international gateway is Rome Leonardo da Vinci Airport, known as Fiumicino (FCO) (30 km / 19 mi south west of Rome, tel. +39 06.65953640).
Florence Airport A. Vespucci, known as Peretola (FLR) (10 km / 6 mi northwest of Florence, phone: +39 055.3061700), has connections to Brussels, Paris, London, Rome, and Milan. Flight time is about 9 hours from New York, 11 hours from Chicago, 12 hours from Dallas (New York), 12 hours from Los Angeles, 2 hours from London (to Milan), and 24 hours from Sydney.
The solution we advise you to reach Assisi by plane is to land in Rome and continue to Assisi by bus or train.
There are daily bus connections from Rome Fiumicino Airport (International Terminal “C”) and Assisi (St. Peter’s Square)
Local Airport – Perugia Sant’Egidio Airport (PEG) (Phone: +39 075.592141) has only daily flights to and from Milan, where direct flights are available to and from most major international destinations.
For those coming from the south, the A1 motorway exit is best Orte, which is linked to Perugia from SS204 (direction Terni) before, and the E45 (or SS3bis) from Terni to Perugia and then. In this case before Perugia, get to Ponte San Giovanni, follow the signs for Assisi, taking the E45, c / o Collestrada on the SS75. Exit at Santa Maria degli Angeli and follow the signs for Assisi.
Coming from the north on the A14 on the Adriatic coast, the best way to reach Assisi is to exit Cesena motorway, then take the E45 to Citta ‘di Castello, then arrive at Collestrada junction. Leave the E45 and take the SS75. Exit at Santa Maria degli Angeli and follow the signs to Assisi.
The best exit to Assisi on the A1 motorway is Valdichiana, where the road enters the SS75bis overlooking Trasimeno Lake in Umbria, before, and then to Perugia. Then get Ponte San Giovanni and head for Assisi, Collestrada on the SS75, exit at Santa Maria degli Angeli and follow the signs for Assisi.